Preferred Name

Tumor Necrosis Factor-alpha
Synonyms

Tumor necrosis factor alpha

TNF-alpha

TNFalpha

Cachectin-Tumor Necrosis Factor

TNF

Tumor Necrosis Factor-alpha (macrophage-derived)

TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 002

Tumor Necrosis Factor Ligand Superfamily Member 2

Tumor Necrosis Factor

TNFA

Cachectin

TNF Superfamily, Member 2

Definitions

Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. (source : MSH)

ID

http://doe-generated-ontology.com/OntoAD#C1456820

altLabel

Tumor necrosis factor alpha

TNF-alpha

TNFalpha

Cachectin-Tumor Necrosis Factor

TNF

Tumor Necrosis Factor-alpha (macrophage-derived)

TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 002

Tumor Necrosis Factor Ligand Superfamily Member 2

Tumor Necrosis Factor

TNFA

Cachectin

TNF Superfamily, Member 2

definition

Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. (source : MSH)

gene_product_encoded_by_gene

http://doe-generated-ontology.com/OntoAD#C0812246

http://doe-generated-ontology.com/OntoAD#C1333196

http://doe-generated-ontology.com/OntoAD#C1336836

gene_product_plays_role_in_biological_process

http://doe-generated-ontology.com/OntoAD#C0007587

http://doe-generated-ontology.com/OntoAD#C0162638

hiddenLabel

TumorNecrosisFactor-alpha

prefixIRI

OntoAD:C1456820

prefLabel

Tumor Necrosis Factor-alpha

subClassOf

http://doe-generated-ontology.com/OntoAD#C0041368

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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.467.972.626 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.276.374.500.800 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014409 RH-MESH LOOM
http://purl.bioontology.org/ontology/CSP/1553-6966 CRISP LOOM
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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.395.930 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.529.972.626 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP18480-1 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004497 LOINC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000043225 PDQ LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.124.900 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.529.374.750.626 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.467.374.500.800 RH-MESH LOOM
http://ccdb.ucsd.edu/SAO/1.2#sao220868685 SAO LOOM
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http://purl.obolibrary.org/obo/IDOMAL_0000783 IDOMAL LOOM
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http://purl.obolibrary.org/obo/OMIT_0015245 OMIT LOOM
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http://purl.obolibrary.org/obo/MESH_D014409 BERO LOOM
http://www.case.edu/ProvCaRe/provcare#TumorNecrosisFactorAlpha NEUROBRG LOOM
http://scai.fraunhofer.de/MSOntology#Tumor_Necrosis_Factor_Alpha MSO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.467.374.750.626 RH-MESH LOOM
http://id.nlm.nih.gov/mesh/D014409 MDM LOOM
http://purl.obolibrary.org/obo/PR_000000134 NIFSTD LOOM
http://purl.obolibrary.org/obo/PR_000000134 IDODEN LOOM
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http://www.phoc.org.cn/pmo/class/PMO_00021544 PMAPP-PMO LOOM
http://uri.neuinfo.org/nif/nifstd/sao220868685 NIFSTD LOOM
http://purl.bioontology.org/ontology/MESH/D014409 MESH LOOM
http://www.ebi.ac.uk/efo/EFO_0003271 EFO LOOM
http://www.ebi.ac.uk/efo/EFO_0003271 BMONT LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571345044435365949 ACVD_ONTOLOGY LOOM