Preferred Name | Tumor Necrosis Factor-alpha | |
Synonyms |
Tumor necrosis factor alpha TNF-alpha TNFalpha Cachectin-Tumor Necrosis Factor TNF Tumor Necrosis Factor-alpha (macrophage-derived) TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 002 Tumor Necrosis Factor Ligand Superfamily Member 2 Tumor Necrosis Factor TNFA Cachectin TNF Superfamily, Member 2 |
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Definitions |
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. (source : MSH) |
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ID |
http://doe-generated-ontology.com/OntoAD#C1456820 |
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altLabel |
Tumor necrosis factor alpha TNF-alpha TNFalpha Cachectin-Tumor Necrosis Factor TNF Tumor Necrosis Factor-alpha (macrophage-derived) TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 002 Tumor Necrosis Factor Ligand Superfamily Member 2 Tumor Necrosis Factor TNFA Cachectin TNF Superfamily, Member 2 |
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definition |
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. (source : MSH) |
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gene_product_encoded_by_gene |
http://doe-generated-ontology.com/OntoAD#C0812246 |
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gene_product_plays_role_in_biological_process | ||
hiddenLabel |
TumorNecrosisFactor-alpha |
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prefixIRI |
OntoAD:C1456820 |
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prefLabel |
Tumor Necrosis Factor-alpha |
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subClassOf |