Preferred Name | Pick Disease of the Brain | |
Synonyms |
Pick's disease with dementia Dementia in Pick's disease Pick's disease PICK DIS syndrome; Pick Circumscribed cerebral atrophy PICK DIS OF THE BRAIN Lobar cerebral atrophy syndrome; Pick, dementia in Circumscribed Lobar Atrophy of the Brain Dementia Due to Pick's Disease pick s disease disease; brain, Pick Pick; disease or syndrome Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions Lobar Atrophy |
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Definitions |
A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Princi (source : MSH) |
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ID |
http://doe-generated-ontology.com/OntoAD#C0236642 |
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altLabel |
Pick's disease with dementia Dementia in Pick's disease Pick's disease PICK DIS syndrome; Pick Circumscribed cerebral atrophy PICK DIS OF THE BRAIN Lobar cerebral atrophy syndrome; Pick, dementia in Circumscribed Lobar Atrophy of the Brain Dementia Due to Pick's Disease pick s disease disease; brain, Pick Pick; disease or syndrome Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions Lobar Atrophy |
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definition |
A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Princi (source : MSH) |
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disease_has_associated_anatomic_site | ||
has_associated_morphology | ||
has_finding_site | ||
has_location |
http://doe-generated-ontology.com/OntoAD#C0039485 http://doe-generated-ontology.com/OntoAD#C0016733 |
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has_manifestation |
http://doe-generated-ontology.com/OntoAD#C0240735 http://doe-generated-ontology.com/OntoAD#C1850496 http://doe-generated-ontology.com/OntoAD#C0085632 |
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has_severity | ||
hiddenLabel |
PickDiseaseOfTheBrain |
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prefixIRI |
OntoAD:C0236642 |
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prefLabel |
Pick Disease of the Brain |
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subClassOf |