Preferred Name |
Apoptosis |
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Synonyms |
apoptotic programmed cell death Apoptosis Pathway Programmed Cell Death Gene-directed cell death Apoptotic Process self destruction of the cell PCD Programmed Cell Death, Type I Mechanism that allows cells to self-destruct when it is necessary programmed cell death by apoptosis apoptotic cell death |
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Definitions |
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis (source : MSH) |
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ID |
http://doe-generated-ontology.com/OntoAD#C0162638 |
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altLabel |
apoptotic programmed cell death Apoptosis Pathway Programmed Cell Death Gene-directed cell death Apoptotic Process self destruction of the cell PCD Programmed Cell Death, Type I Mechanism that allows cells to self-destruct when it is necessary programmed cell death by apoptosis apoptotic cell death |
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biological_process_has_associated_location | ||
biological_process_involves_gene_product |
http://doe-generated-ontology.com/OntoAD#C0291573 http://doe-generated-ontology.com/OntoAD#C0389726 http://doe-generated-ontology.com/OntoAD#C0385242 http://doe-generated-ontology.com/OntoAD#C0297981 http://doe-generated-ontology.com/OntoAD#C0021757 http://doe-generated-ontology.com/OntoAD#C0021753 http://doe-generated-ontology.com/OntoAD#C1456820 http://doe-generated-ontology.com/OntoAD#C0010656 |
|
definition |
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis (source : MSH) |
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hiddenLabel |
Apoptosis |
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prefixIRI |
OntoAD:C0162638 |
|
prefLabel |
Apoptosis |
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process_involves_gene |
http://doe-generated-ontology.com/OntoAD#C0812246 http://doe-generated-ontology.com/OntoAD#C1366532 http://doe-generated-ontology.com/OntoAD#C1332090 http://doe-generated-ontology.com/OntoAD#C1332323 http://doe-generated-ontology.com/OntoAD#C1332324 http://doe-generated-ontology.com/OntoAD#C1705952 http://doe-generated-ontology.com/OntoAD#C1418986 http://doe-generated-ontology.com/OntoAD#C1336646 http://doe-generated-ontology.com/OntoAD#C1705543 http://doe-generated-ontology.com/OntoAD#C1364818 |
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subClassOf |
http://doe-generated-ontology.com/OntoAD#C0007587 |