loading...| Preferred Name |
Prion Diseases |
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| Synonyms |
Prion-associated disorders Spongiform Encephalopathies, Transmissible |
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| Definitions |
A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as un (source : MSH) |
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| ID |
http://doe-generated-ontology.com/OntoAD#C0162534 |
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| altLabel |
Prion-associated disorders DEMENTIAS TRANSM PRION PROTEIN DIS Transmissible Dementias Encéphalopathies spongiformes transmissibles PRION DIS Maladies à prion Prion Disease Pathway Démences transmissibles Troubles associés aux prions prion disease of central nervous system ENCEPH SPONGIFORM TRANSM EST (Encéphalopathie Spongiforme Transmissible) PRION IND DIS prion disease Prion Protein Diseases Spongiform encephalopathy Prion-Induced Disorder E-3B0 PRION DISEASES Maladie a prions Spongiform Encephalopathies, Transmissible |
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| definition |
A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as un (source : MSH) groupe d'humain dégénératif génétique, infectieux, ou sporadique et de troubles de système nerveux d'animal associé PRIONS anormal. Ces maladies sont caractérisées par la conversion de la protéine prions normale à une configuration anormale via un processus post-translationnel. Chez les humains, ces affections présentent généralement la DÉMENCE; ATAXIE; et un résultat fatal. Les caractéristiques de Pathologique incluent un ¤slspongiform¤sl ¤slencephalopathy¤sl sans évidence d'inflammation. La li (source : CISMeF) |
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| disease_has_associated_anatomic_site | ||
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| has_associated_morphology | ||
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| has_finding_site | ||
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| hiddenLabel |
MaladiesÀPrions PrionDiseases |
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| prefixIRI |
OntoAD:C0162534 |
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| prefLabel |
Prion Diseases Maladies à prions |
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| subClassOf |
http://doe-generated-ontology.com/OntoAD#C0349723 http://doe-generated-ontology.com/OntoAD#C0206307 http://doe-generated-ontology.com/OntoAD#C1446648 |