Preferred Name

Tretinoin
Synonyms

All-trans Vitamin A Acid

Tretinoinum

all-trans-Retinoic Acid

Tretinoin cytostatic

beta-Retinoic Acid

Trans Vitamin A Acid

TRA

Vitamin A Acid

trans-Retinoic Acid

retinoids tretinoin

Retinoic Acid

ATRA

Definitions

An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE). (source : MSH)

ID

http://doe-generated-ontology.com/OntoAD#C0040845

altLabel

All-trans Vitamin A Acid

Tretinoinum

all-trans-Retinoic Acid

Tretinoin cytostatic

beta-Retinoic Acid

Trans Vitamin A Acid

TRA

Vitamin A Acid

trans-Retinoic Acid

retinoids tretinoin

Retinoic Acid

ATRA

chemical_or_drug_has_physiologic_effect

http://doe-generated-ontology.com/OntoAD#C0017263

contraindicated_drug

http://doe-generated-ontology.com/OntoAD#C0013182

definition

An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE). (source : MSH)

hiddenLabel

Tretinoin

prefixIRI

OntoAD:C0040845

prefLabel

Tretinoin

subClassOf

http://doe-generated-ontology.com/OntoAD#C0035339

http://doe-generated-ontology.com/OntoAD#C0358061

http://doe-generated-ontology.com/OntoAD#C0022585

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Mapping To Ontology Source
http://purl.bioontology.org/ontology/ATC/L01XF01 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.767.261.700.780 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C900 BERO LOOM
http://purl.bioontology.org/ontology/RCD/x03pf RCD LOOM
http://purl.bioontology.org/ontology/MESH/D014212 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.849.131.495.818.800 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146871 NDFRT LOOM
http://www.co-ode.org/ontologies/galen#Tretinoin GALEN LOOM
https://go.drugbank.com/drugs/DB00755 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.392.368.367.379.249.700.860.500 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB00755 FTC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12512 OCHV LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C900 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.326.271.665.202.495.818.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000041258 PDQ LOOM
http://purl.obolibrary.org/obo/CHEBI_15367 PDRO LOOM
http://purl.obolibrary.org/obo/MESH_D014212 BERO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387305002 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/OMIT_0015051 OMIT LOOM
http://purl.bioontology.org/ontology/VANDF/4018550 VANDF LOOM
http://purl.bioontology.org/ontology/SNMI/C-92010 SNMI LOOM
http://purl.bioontology.org/ontology/ATC/D10AD01 ATC LOOM
http://purl.obolibrary.org/obo/MCBCC_0000270#Tretinoin MCBCC LOOM
http://purl.jp/bio/4/id/200906081568041395 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0040845 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/10753 RXNORM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016677 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014212 RH-MESH LOOM