Preferred Name | Transforming Growth Factor beta | |
Synonyms |
TGF-beta Milk Growth Factor Bone-Derived Transforming Growth Factor Platelet Transforming Growth Factor TGF B TGFbeta |
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Definitions |
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3 (source : MSH) |
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ID |
http://doe-generated-ontology.com/OntoAD#C0040690 |
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altLabel |
TGF-beta Milk Growth Factor Bone-Derived Transforming Growth Factor Platelet Transforming Growth Factor TGF B TGFbeta |
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definition |
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3 (source : MSH) |
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gene_product_encoded_by_gene | ||
gene_product_plays_role_in_biological_process | ||
hiddenLabel |
TransformingGrowthFactorBeta |
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prefixIRI |
OntoAD:C0040690 |
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prefLabel |
Transforming Growth Factor beta |
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subClassOf |