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Bilingual Ontology of Alzheimer's Disease and Related Diseases
Last uploaded:
December 2, 2013
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| Id | http://doe-generated-ontology.com/OntoAD#C0003595
http://doe-generated-ontology.com/OntoAD#C0003595
|
|---|---|
| Preferred Name | Apolipoprotein E |
| Definitions |
A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency (source : MSH)
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| Synonyms |
Apolipoproteins E
apoE
Apo-E
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency (source : MSH) |
|---|---|
| altLabel |
Apolipoproteins E
apoE
Apo-E
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| prefLabel | Apolipoprotein E
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| hiddenLabel | ApolipoproteinE
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| prefixIRI | OntoAD:C0003595
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| gene_product_encoded_by_gene | |
| gene_product_malfunction_associated_with_disease | |
| subClassOf | |
| gene_product_plays_role_in_biological_process | |
| type | |
| gene_product_has_biochemical_function |
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