Preferred Name | Alzheimer's Disease | |
Synonyms |
SDAT AD dementia of Alzheimer's type dementia; Alzheimer ALZHEIMER DIS Alzheimer dementia dementia of the Alzheimer type Dementia in Alzheimer's disease Alzheimers disease sclerosis; Alzheimer senile dementia of the Alzheimer type (SDAT) alzheimers dementia Alzheimer syndrome Alzheimer-type dementia (ADT) Alzheimer Alzheimer dementia (AD) Primary Senile Degenerative Dementia ALZHEIMERS DIS DAT Alzheimer’s disease Dementia of Alzheimers Type primary; degenerative, dementia Dementia, Alzheimer Type simple senile dementia Dementia in Alzheimer's Dementia, Senile Alzheimer's disease pathology disease Alzheimer DAT Dementia Alzheimer's type AD Alzheimer's disease Dementia in Alzheimer's dis Senile Dementia, Alzheimer Type Alzheimer's dementia Alzheimer disease AD dementia Alzheimer's pathology |
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Definitions |
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) (source : MSH) |
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ID |
http://doe-generated-ontology.com/OntoAD#C0002395 |
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altLabel |
SDAT AD dementia of Alzheimer's type dementia; Alzheimer ALZHEIMER DIS Alzheimer dementia dementia of the Alzheimer type Dementia in Alzheimer's disease Alzheimers disease sclerosis; Alzheimer senile dementia of the Alzheimer type (SDAT) alzheimers dementia Alzheimer syndrome Alzheimer-type dementia (ADT) Alzheimer Alzheimer dementia (AD) Primary Senile Degenerative Dementia ALZHEIMERS DIS DAT Alzheimer’s disease Dementia of Alzheimers Type primary; degenerative, dementia Dementia, Alzheimer Type simple senile dementia Dementia in Alzheimer's Dementia, Senile Alzheimer's disease pathology disease Alzheimer DAT Dementia Alzheimer's type AD Alzheimer's disease Dementia in Alzheimer's dis Senile Dementia, Alzheimer Type Alzheimer's dementia Alzheimer disease AD dementia Alzheimer's pathology |
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associated_with_malfunction_of_gene_product |
http://doe-generated-ontology.com/OntoAD#C0003595 http://doe-generated-ontology.com/OntoAD#C0291573 http://doe-generated-ontology.com/OntoAD#C0528480 http://doe-generated-ontology.com/OntoAD#C2700455 http://doe-generated-ontology.com/OntoAD#C0055966 http://doe-generated-ontology.com/OntoAD#C0699919 http://doe-generated-ontology.com/OntoAD#C0299212 |
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clinically_associated_with | ||
clinically_similar |
http://doe-generated-ontology.com/OntoAD#C0276496 http://doe-generated-ontology.com/OntoAD#C0338448 http://doe-generated-ontology.com/OntoAD#C0338449 http://doe-generated-ontology.com/OntoAD#C0338446 http://doe-generated-ontology.com/OntoAD#C0338445 |
|
definition |
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) (source : MSH) |
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disease_has_associated_anatomic_site | ||
disease_has_associated_gene |
http://doe-generated-ontology.com/OntoAD#C1412481 http://doe-generated-ontology.com/OntoAD#C1413514 http://doe-generated-ontology.com/OntoAD#C2697954 http://doe-generated-ontology.com/OntoAD#C1418986 http://doe-generated-ontology.com/OntoAD#C2827465 http://doe-generated-ontology.com/OntoAD#C1423544 |
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has_associated_morphology | ||
has_finding_site | ||
has_location |
http://doe-generated-ontology.com/OntoAD#C0242202 |
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has_manifestation | ||
has_severity | ||
hiddenLabel |
Alzheimer'sDisease |
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manifestation_of | ||
may_be_prevented_by | ||
may_be_treated_by |
http://doe-generated-ontology.com/OntoAD#C0039245 http://doe-generated-ontology.com/OntoAD#C0772415 http://doe-generated-ontology.com/OntoAD#C0527316 http://doe-generated-ontology.com/OntoAD#C0042291 http://doe-generated-ontology.com/OntoAD#C0649350 |
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prefixIRI |
OntoAD:C0002395 |
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prefLabel |
Alzheimer's Disease |
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subClassOf |
http://doe-generated-ontology.com/OntoAD#C0349723 |