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Ontology for Newborn Screening Follow-up and Translational Research
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September 4, 2014
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Id | http://purl.obolibrary.org/obo/pr.owl#PR_000012234
http://purl.obolibrary.org/obo/pr.owl#PR_000012234
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Preferred Name | phenylalanine-4-hydroxylase |
Definitions |
A protein that is a translation product of the PAH gene or a 1:1 ortholog thereof.
This class name denotes the phenylalanine-4-hydroxylase enzyme monomer, *not* the phenylalanine-4-hydroxylase complex which is a homomonomer (a dimer or tetramer consisting of 2 or 4 phenylalanine-4-hydroxylase monomers) and which is the bearer of the phenylalanine-4-monoxygenase activity (GO:00016714).
Note: In the literature, in the case of homomonomeric enzyme (protein) complexes, the same names are used for both monomers and corresponding protein complexes, e.g. phenylalanine-4-hydroxylase is interghangeably used both for catalytically inactive enzyme monomer and for catalytically active protein complex.
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Synonyms |
4-hydroxylase phenylalanine
Phe-4-monooxygenase
hydroxylase, phenylalanine
phenylalanine hydroxylase
PAH
phenylalaninase
PheOH
PheH
phenylalanine 4 monooxygenase
phenylalanine 4-monooxygenase monomer
phenylalanine 4 hydroxylase
phenylalanine 4-monooxygenase
phenylalanine-4-hydroxylase monomer
4-monooxygenase, phenylalanine
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | A protein that is a translation product of the PAH gene or a 1:1 ortholog thereof. This class name denotes the phenylalanine-4-hydroxylase enzyme monomer, *not* the phenylalanine-4-hydroxylase complex which is a homomonomer (a dimer or tetramer consisting of 2 or 4 phenylalanine-4-hydroxylase monomers) and which is the bearer of the phenylalanine-4-monoxygenase activity (GO:00016714). Note: In the literature, in the case of homomonomeric enzyme (protein) complexes, the same names are used for both monomers and corresponding protein complexes, e.g. phenylalanine-4-hydroxylase is interghangeably used both for catalytically inactive enzyme monomer and for catalytically active protein complex. |
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altLabel |
4-hydroxylase phenylalanine
Phe-4-monooxygenase
hydroxylase, phenylalanine
phenylalanine hydroxylase
PAH
phenylalaninase
PheOH
PheH
phenylalanine 4 monooxygenase
phenylalanine 4-monooxygenase monomer
phenylalanine 4 hydroxylase
phenylalanine 4-monooxygenase
phenylalanine-4-hydroxylase monomer
4-monooxygenase, phenylalanine
See more
See less
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label | phenylalanine-4-hydroxylase
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comment | This class name denotes the phenylalanine-4-hydroxylase enzyme monomer, *not* the phenylalanine-4-hydroxylase complex which is a homomonomer (a dimer or tetramer consisting of 2 or 4 phenylalanine-4-hydroxylase monomers) and which is the bearer of the phenylalanine-4-monoxygenase activity (GO:00016714).
Note: In the literature, in the case of homomonomeric enzyme (protein) complexes, the same names are used for both monomers and corresponding protein complexes, e.g. phenylalanine-4-hydroxylase is interghangeably used both for catalytically inactive enzyme monomer and for catalytically active protein complex.
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prefLabel | phenylalanine-4-hydroxylase
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prefixIRI | PRO:PR_000012234
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subClassOf | |
editorialNote | Curation status: Imported from the Protein Ontology (PRO).
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type |
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