Ontology for MicroRNA Target

Last uploaded: January 5, 2021
Preferred Name

RNA interference
Synonyms
Definitions

The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.

ID

http://purl.obolibrary.org/obo/GO_0016246

alternative term

posttranscriptional gene silencing by siRNA

RNAi

definition

The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.

imported from

http://purl.obolibrary.org/obo/go.owl

label

RNA interference

prefixIRI

GO:0016246

prefLabel

RNA interference

seeAlso

Wikipedia:RNA_interference

subClassOf

http://purl.obolibrary.org/obo/GO_0035194

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http://purl.obolibrary.org/obo/GO_0016246 GO SAME_URI
http://www.phoc.org.cn/pmo/class/PMO_00065942 PMAPP-PMO LOOM
http://purl.jp/bio/4/id/200906093715118470 IOBC LOOM
http://purl.obolibrary.org/obo/MI_0256 MI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D034622 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D034622 MESH LOOM
http://www.projecthalo.com/aura#RNA-Interference AURA LOOM
http://purl.obolibrary.org/obo/NCIT_C20153 BERO LOOM
http://localhost/plosthes.2017-1#10525 PLOSTHES LOOM
http://purl.obolibrary.org/obo/GO_0016246 GO-EXT LOOM
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https://pat.nichd.nih.gov/patinvestigativetechniques/IT.06.05 PATIT LOOM
http://purl.obolibrary.org/obo/MESH_D034622 BERO LOOM
http://www.bootstrep.eu/ontology/GRO#RNAInterference GRO LOOM
http://purl.bioontology.org/ontology/CSP/5004-0070 CRISP LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20153 NCIT LOOM
http://purl.org/obo/owl/GO#GO_0016246 BIOMODELS LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#G05.355.315.203.374.790 RH-MESH LOOM