Online Mendelian Inheritance in Man

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/OMIM/608902
http://purl.bioontology.org/ontology/OMIM/608902
Preferred Name

DRUG METABOLISM, POOR, CYP2D6-RELATED
Synonyms
DEBRISOQUINE, POOR METABOLISM OF
NORTRIPTYLINE, POOR METABOLISM OF
CODEINE, ULTRARAPID METABOLISM OF
SPARTEINE, POOR METABOLISM OF
DRUG METABOLISM, ULTRARAPID, CYP2D6-RELATED
DEBRISOQUINE, ULTRARAPID METABOLISM OF
Type http://www.w3.org/2002/07/owl#Class

All Properties

altLabel
DEBRISOQUINE, POOR METABOLISM OF
NORTRIPTYLINE, POOR METABOLISM OF
CODEINE, ULTRARAPID METABOLISM OF
SPARTEINE, POOR METABOLISM OF
DRUG METABOLISM, ULTRARAPID, CYP2D6-RELATED
DEBRISOQUINE, ULTRARAPID METABOLISM OF
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prefLabel
DRUG METABOLISM, POOR, CYP2D6-RELATED
Gene Symbol
P450DB1
CPD6
CYP2D6
Scope Statement
CYP2D6 enzyme is located in the endoplasmic reticulum of the liver [MISCELLANEOUS]
Caused by mutation in the cytochrome P450, subfamily IID6 gene (CYP2D6, 124030.0001) [MOLECULAR BASIS]
Ultrarapid metabolizers have multiple copies of the CYP2D6 gene (124030.0007) [MISCELLANEOUS]
CYP2D6 represents about 1% of total liver cytochrome P450 content [MISCELLANEOUS]
type
Has manifestation
tui
T047
T033
Gene Locus
22q13.1
MIMTYPEMEANING
Phenotype description, molecular basis known.
notation
608902
Semantic type UMLS property
Has inheritance type
cui
C1837159
C1837154
C1837158
C1837156
C1837155
C1837160
C1837157
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OMIM Entry Type
3
OMIM MimType Value
pound
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