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Ontology of Host-Pathogen Interactions
Last uploaded:
September 30, 2019
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| Id | http://purl.obolibrary.org/obo/UBERON_0001199
http://purl.obolibrary.org/obo/UBERON_0001199
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|---|---|
| Preferred Name | mucosa of stomach |
| Definitions |
The mucosal layer that lines the stomach.
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| Synonyms |
Magenschleimhaut
tunica mucosa gastris
organ mucosa of stomach
tunica mucosa (gaster)
gastric mucous membrane
mucous membrane of ventriculus
mucosa of ventriculus
tunica mucosa gastricae
stomach organ mucosa
ventriculus mucosa of organ
mucous membrane of stomach
gastric mucosa
stomach mucosa
organ mucosa of ventriculus
mucosa of organ of ventriculus
stomach mucous membrane
mucosa of organ of stomach
ventriculus organ mucosa
stomach mucosa of organ
ventriculus mucous membrane
ventriculus mucosa
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
mucosa of stomach
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|---|---|
| prefLabel |
mucosa of stomach
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| 数据库_交叉_引用 |
CALOHA:TS-0404
BTO:0001308
galen:GastricMucosa
FMA:14907
OpenCyc:Mx8NhB4rvcD6KJwpEbGdrcN5Y29ycB4rvmKNOpwpEbGdrcN5Y29ycB4rvVj5FpwpEbGdrcN5Y29ycB4rvVjlqpwpEbGdrcN5Y29ycA
EMAPA:35817
UMLS:C0017136
NCIT:C32656
MESH:A03.492.766.440
GAID:321
MA:0002683
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|
| notation |
UBERON:0001199
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| in_subset | |
| depicted_by | |
| has_related_synonym |
Magenschleimhaut
tunica mucosa gastris
|
| id |
UBERON:0001199
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| 有_obo_命名空间 |
uberon
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| part_of | |
| external_definition |
The gastric mucosa is the mucous membrane layer of the stomach which contains the glands and the gastric pits. In men it is about 1 mm thick and its surface is smooth, soft, and velvety. It consists of epithelium, lamina propria, and the muscularis mucosae. In its fresh state, it is of a pinkish tinge at the pyloric end and of a red or reddish-brown color over the rest of its surface. In infancy it is of a brighter hue, the vascular redness being more marked. It is thin at the cardiac extremity, but thicker toward the pylorus. During the contracted state of the organ it is thrown into numerous plaits or rugae, which, for the most part, have a longitudinal direction, and are most marked toward the pyloric end of the stomach, and along the greater curvature. These folds are entirely obliterated when the organ becomes distended. When examined with a lens, the inner surface of the mucous membrane presents a peculiar honeycomb appearance from being covered with funnel-like depressions or foveolae of a polygonal or hexagonal form, which vary from 0.12 to 0.25 mm. in diameter. These are the ducts of the gastric glands, and at the bottom of each may be seen one or more minute orifices, the openings of the gland tubes. Gastric glands are simple or branched tubular glands that emerge on the deeper part of the gastric foveola, inside the gastric areas and outlined by the folds of the mucosa. There are three types of glands: cardiac glands (in the proximal part of the stomach), oxyntic glands (the dominating type of gland), and pyloric glands. The cardiac glands mainly contain mucus producing cells. The bottom part of the oxyntic glands is dominated by zymogen (chief) cells that produce pepsinogen (an inactive precursor of the pepsin enzyme). Parietal cells, which secrete hydrochloric acid are scattered in the glands, with most of them in the middle part. The upper part of the glands consist of mucous neck cells; in this part the dividing cells are seen. The pyloric glands contain mucus-secreting cells. Several types of endocrine cells are found in all regions of the gastric mucosa. In the pyloric glands contain gastrin producing cells (G cells); this hormone stimulates acid production from the parietal cells. ECL (enterochromaffine-like) cells, found in the oxyntic glands release histamine, which also is a powerful stimulant of the acid secretion. The A cells produce glucagon, which mobilizes the hepatic glycogen, and the enterochromaffin cells that produce serotonin, which stimulates the contraction of the smooth muscles. The surface of the mucous membrane is covered by a single layer of columnar epithelium . This epithelium commences very abruptly at the cardiac orifice, where there is a sudden transition from the stratified epithelium of the esophagus. The epithelial lining of the gland ducts is of the same character and is continuous with the general lining of the stomach. [WP,unvetted][Wikipedia:Gastric_mucosa].
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| 文本定义 |
The mucosal layer that lines the stomach.
|
| subClassOf | |
| type | |
| has_exact_synonym |
organ mucosa of stomach
tunica mucosa (gaster)
gastric mucous membrane
mucous membrane of ventriculus
mucosa of ventriculus
tunica mucosa gastricae
stomach organ mucosa
ventriculus mucosa of organ
mucous membrane of stomach
gastric mucosa
stomach mucosa
organ mucosa of ventriculus
mucosa of organ of ventriculus
stomach mucous membrane
mucosa of organ of stomach
ventriculus organ mucosa
stomach mucosa of organ
ventriculus mucous membrane
ventriculus mucosa
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