Ontology of Drug Adverse Events

Last uploaded: January 12, 2019
Preferred Name

cerebellum

Synonyms

parencephalon

corpus cerebelli

infratentorial region

epencephalon-1

Definitions

Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA].

ID

http://purl.obolibrary.org/obo/UBERON_0002037

contributes to morphology of

http://purl.obolibrary.org/obo/UBERON_0001895

database_cross_reference

http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=643

UMLS:C1268981

EFO:0000327

DHBA:10656

GAID:595

MESH:D002531

OpenCyc:Mx4rvl1eipwpEbGdrcN5Y29ycA

MAT:0000110

VHOG:0000024

BTO:0000232

BM:CB

EHDAA2:0000232

UMLS:C0007765

EV:0100293

CALOHA:TS-0125

BAMS:Cb

TAO:0000100

MBA:512

EMAPA:17787

AAO:0010485

FMA:67944

MIAA:0000110

HBA:4696

MA:0000198

ZFA:0000100

BAMS:CB

XAO:0003098

http://uri.neuinfo.org/nif/nifstd/birnlex_1489

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12445

http://www.snomedbrowser.com/Codes/Details/180924008

http://en.wikipedia.org/wiki/Cerebellum

http://linkedlifedata.com/resource/umls/id/C0007765

http://linkedlifedata.com/resource/umls/id/C1268981

http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=643

depicted_by

http://upload.wikimedia.org/wikipedia/commons/a/a7/Cerebellum_NIH.png

develops_from

http://purl.obolibrary.org/obo/UBERON_0006215

dubious_for_taxon

http://purl.obolibrary.org/obo/NCBITaxon_117569

external_definition

Dorsal part of the hindbrain that coordinates muscle movement, posture, and balance.[AAO]

Specialized brain region derived from the dorsal metencephalon (anterior hindbrain, and perhaps including posterior midbrain) and becoming distinctive late in the segmentation period. Kimmel et al, 1995.[TAO]

external_ontology_notes

almost all AOs agree that the cerebellum is part of the hindbrain (sometimes specifically part of the metencephalon, which, when present, is part of the hindbrain). However, ABA has cerebellum and brain stem as partof siblings, with the hindbrain part of the brainstem

has exact synonym

epencephalon-1

has_broad_synonym

infratentorial region

has_obo_namespace

uberon

has_related_synonym

parencephalon

corpus cerebelli

has_relational_adjective

cerebellar

homology_notes

However, although the lamprey possesses a region comparable to the cerebellum and display expression of LjFgf8/17 at the MHB (midbrain hindbrain boundary), it does not have Purkinje cells and cerebellar nuclei, as well as components of the rhombic lip-derived cerebellar and pre-cerebellar systems. It is noteworthy that the latter structures require specific expression of Pax6 in the rhombic lip of the gnathostome hindbrain. Interestingly, the lamprey rhombic lip does not express Pax6. Thus, it is tempting to speculate that in vertebrate evolution the rostral hindbrain is incapable of differentiating into the cerebellum before the co-option of Pax6 in that region. In other words, cerebellum has been brought about as an evolutionary innovation in gnathostomes, based on exaptation of MHB, rhombic lip, and some regulatory gene expression already present in the vertebrate common ancestor.[well established][VHOG]

id

UBERON:0002037

imported from

http://purl.obolibrary.org/obo/uberon.owl

http://purl.obolibrary.org/obo/oae.owl

in subset

http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#uberon_slim

http://purl.oboInOwllibrary.org/oboInOwl/uberon#uberon_slim

http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#pheno_slim

http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#vertebrate_core

http://purl.oboInOwllibrary.org/oboInOwl/uberon#vertebrate_core

http://purl.oboInOwllibrary.org/oboInOwl/uberon/core#efo_slim

label

cerebellum

notation

UBERON:0002037

part_of

http://purl.obolibrary.org/obo/UBERON_0002028

http://purl.obolibrary.org/obo/UBERON_0001895

prefLabel

cerebellum

present_in_taxon

http://purl.obolibrary.org/obo/NCBITaxon_117569

taxon_notes

The absence of a cerebellum in hagfishes and lampreys appears to be the only exception [to the rule that vertebrates possess the same number of brain divisions]. Both hagfishes and lampreys do possess a thin band of cells located medial to the lateral line centers of the medulla (Ronan and Northcutt, 1998), which has been interpreted as a primitive cerebellum (Larsell, 1967), but more recent experimental studies (Kishida et al., 1987; Weigle and Northcutt, 1998) fail to support Larsell's claim[http://icb.oxfordjournals.org/content/42/4/743.full]

textual definition

Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA].

treeView

http://purl.obolibrary.org/obo/UBERON_0006215

http://purl.obolibrary.org/obo/UBERON_0002028

http://purl.obolibrary.org/obo/UBERON_0001895

subClassOf

http://purl.obolibrary.org/obo/UBERON_0002616

http://purl.obolibrary.org/obo/UBERON_0010314

spatially_disjoint_from

http://purl.obolibrary.org/obo/UBERON_0002298

http://purl.obolibrary.org/obo/UBERON_0001893

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Delete Mapping To Ontology Source
http://www.co-ode.org/ontologies/galen#Cerebellum GALEN LOOM
http://purl.obolibrary.org/obo/VHOG_0000024 VHOG LOOM
http://purl.obolibrary.org/obo/MFO_0002360 MFO LOOM
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http://www.semanticweb.org/ontologies/STO.owl#d5f69e7_2d86_4832_a996_203e34565dc5 STO-DRAFT LOOM
http://doe-generated-ontology.com/OntoPneumo#Cervelet ONTOPNEUMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002531 RH-MESH LOOM
http://purl.obolibrary.org/obo/TAO_0000100 TAO LOOM
http://purl.obolibrary.org/obo/EHDAA2_0000232 EHDAA2 LOOM
http://www.semanticweb.org/ontologies/2012/11/abnormalities.owl#phenodb:1803 IFAR LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0007765 OCHV LOOM
http://purl.obolibrary.org/obo/BTO_0000232 BTO LOOM
http://purl.obolibrary.org/obo/BTO_0000232 DTO LOOM
http://purl.org/sig/ont/fma/fma67944 FMA LOOM
http://purl.org/sig/ont/fma/fma67944 ROO LOOM
http://www.ifomis.org/acgt/1.0#Cerebellum ACGT-MO LOOM
http://www.semanticweb.org/pallabi.d/ontologies/2014/2/untitled-ontology-11#Cerebellum MCCL LOOM
urn:absolute:RadiationOncologyStructuresOntology#Cerebellum ROS LOOM
http://mouse.brain-map.org/atlas/index.html#CB ABA-AMB LOOM
http://purl.jp/bio/4/id/200906026328289046 IOBC LOOM
http://www.semanticweb.org/rjyy/ontologies/2015/5/ESSO#Cerebellum ESSO LOOM
http://uri.neuinfo.org/nif/nifstd/birnlex_1489 NIFSTD LOOM
http://uri.interlex.org/fsl/uris/atlases/MNI/labels/1 NIFSTD LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12445 NCIT LOOM
http://purl.obolibrary.org/obo/MAT_0000110 MAT LOOM
http://scai.fraunhofer.de/AlzheimerOntology#cerebellum ADO LOOM
http://purl.org/obo/owl/FMA#FMA_67944 SDO LOOM
http://purl.obolibrary.org/obo/XAO_0003098 XAO LOOM
http://purl.obolibrary.org/obo/XAO_0003098 XPO LOOM
http://api.brain-map.org/api/v2/data/Structure/512 NIFSTD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A08.186.211.132.810.428.200 RH-MESH LOOM
http://purl.obolibrary.org/obo/ZFA_0000100 UPHENO LOOM
http://purl.obolibrary.org/obo/ZFA_0000100 ZP LOOM
http://purl.obolibrary.org/obo/ZFA_0000100 ZFA LOOM
http://radlex.org/RID/RID6815 RADLEX LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2651 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/LP7125-0 LOINC LOOM
http://www.semanticweb.org/ontologies/2009/9/Ontology1255357986125.owl#Cerebellum BRCT LOOM
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http://scai.fraunhofer.de/MSOntology#Cerebellum MSO LOOM
http://localhost/plosthes.2017-1#1589 PLOSTHES LOOM
http://neuromorpho.org/ontologies/vertebrateH.owl#NMOBr_424 NMOBR LOOM
http://purl.bioontology.org/ontology/MESH/D002531 MESH LOOM
http://purl.org/obo/owlapi/fma#FMA_67944 BIOMODELS LOOM
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http://purl.obolibrary.org/obo/UBERON_0002037 EFO SAME_URI
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http://purl.obolibrary.org/obo/UBERON_0002037 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002037 CL LOOM
http://purl.obolibrary.org/obo/UBERON_0002037 CL SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002037 OBA LOOM
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http://purl.obolibrary.org/obo/UBERON_0002037 OAE LOOM
http://purl.obolibrary.org/obo/UBERON_0002037 OAE SAME_URI
http://purl.bioontology.org/ontology/RCD/7N004 RCD LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002958 LOINC LOOM
http://www.projecthalo.com/aura#Cerebellum AURA LOOM
http://www.case.edu/EpSO.owl#Cerebellum EPSO LOOM
http://purl.obolibrary.org/obo/EMAPA_17787 EMAPA LOOM
http://www.semanticweb.org/ontologies/2009/3/ontoDPN.owl#Cervelet_F EPO LOOM
http://purl.obolibrary.org/obo/MA_0000198 MA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A08.186.211.865.428.200 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Cerebellum SYN LOOM
http://doe-generated-ontology.com/OntoAD#C0007765 ONTOAD LOOM
http://purl.bioontology.org/ontology/CSP/0480-0932 CRISP LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Cerebellum APANEUROCLUSTER LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Cerebellum APAONTO LOOM
http://purl.obolibrary.org/obo/FMA_67944 ONTONEO LOOM