Ontology of Drug Adverse Events

Last uploaded: January 12, 2019
Preferred Name

Sirolimus [Chemical/Ingredient]
Synonyms
ID

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000006605

code

C23558

Display_Name

Sirolimus

imported from

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl

label

Sirolimus [Chemical/Ingredient]

MeSH_CUI

M0029863

MeSH_Definition

A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.

MeSH_DUI

D020123

MeSH_Name

Sirolimus

NUI

N0000006605

prefixIRI

NDF-RT:N0000006605

prefLabel

Sirolimus [Chemical/Ingredient]

RxNorm_CUI

35302

RxNorm_Name

Sirolimus

Synonym

Rapamycin

UMLS_CUI

C0072980

subClassOf

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000007529

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