Ontology of Drug Adverse Events

Last uploaded: January 12, 2019
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Preferred Name

Thalidomide [Chemical/Ingredient]
Synonyms
ID

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000006367
code

C23082
Display_Name

Thalidomide
imported from

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl
label

Thalidomide [Chemical/Ingredient]
MeSH_CUI

M0021267
MeSH_Definition

A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppresive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
MeSH_DUI

D013792
MeSH_Name

Thalidomide
NUI

N0000006367
prefixIRI

NDF-RT:N0000006367
prefLabel

Thalidomide [Chemical/Ingredient]
RxNorm_CUI

10432
RxNorm_Name

Thalidomide
Synonym

1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-
UMLS_CUI

C0039736
subClassOf

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000007753

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000007930
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