Ontology of Drug Adverse Events

Last uploaded: January 12, 2019
Preferred Name

Rifampin [Chemical/Ingredient]
Synonyms
ID

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000006026

code

C22396

Display_Name

Rifampin

imported from

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl

label

Rifampin [Chemical/Ingredient]

MeSH_CUI

M0019110

MeSH_Definition

A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)

MeSH_DUI

D012293

MeSH_Name

Rifampin

NUI

N0000006026

prefixIRI

NDF-RT:N0000006026

prefLabel

Rifampin [Chemical/Ingredient]

RxNorm_CUI

9384

RxNorm_Name

Rifampin

Synonym

Rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)-

Benemycin

Rifampicin

UMLS_CUI

C0035608

subClassOf

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000007911

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