Ontology of Drug Adverse Events

Last uploaded: January 12, 2019
Preferred Name

Phenytoin [Chemical/Ingredient]
Synonyms
ID

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000006023

code

C22390

Display_Name

Phenytoin

imported from

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl

label

Phenytoin [Chemical/Ingredient]

MeSH_CUI

M0016580

MeSH_Definition

An anticonvulsant that is used in a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.

MeSH_DUI

D010672

MeSH_Name

Phenytoin

NUI

N0000006023

prefixIRI

NDF-RT:N0000006023

prefLabel

Phenytoin [Chemical/Ingredient]

RxNorm_CUI

8183

RxNorm_Name

Phenytoin

Synonym

Diphenylhydantoin

2,4-Imidazolidinedione, 5,5-diphenyl-

5,5-Diphenylhydantoin

Fenitoin

UMLS_CUI

C0031507

subClassOf

http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000007970

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