Beta Cell Genomics Ontology

Last uploaded: August 20, 2015
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Id http://purl.obolibrary.org/obo/CL_0000771
http://purl.obolibrary.org/obo/CL_0000771
Preferred Name

eosinophil
Definitions
Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte.
Synonyms
polymorphonuclear leukocyte
polymorphonuclear leucocyte
eosinophilic leukocyte
eosinocyte
eosinophilic granulocyte
eosinophilic leucocyte
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive.
label
eosinophil
comment
Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte.
prefLabel
eosinophil
database_cross_reference
CALOHA:TS-0279
BTO:0000399
FMA:62861
has plasma membrane part
has part
has_obo_namespace
cell
prefixIRI
CL:0000771
subClassOf
imported from
type
has_broad_synonym
polymorphonuclear leukocyte
polymorphonuclear leucocyte
has_exact_synonym
eosinophilic leukocyte
eosinocyte
eosinophilic granulocyte
eosinophilic leucocyte
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