Ontology of Biological Attributes

Last uploaded: September 12, 2024
Preferred Name

Decreased response to growth hormone stimulation test
Synonyms
Definitions

GH stimulation tests are performed with various stimuli, such as insulin, L-dopa, arginine, and growth hormone releasing hormone (GHRH). The test using insulin as a stimulus is classically recommended, but this test has potential risks such as hypoglycemia. The effects of growth hormone are mediated almost exclusively by insulin-like growth factor 1(IGF-1), which is produced primarily in the liver. Growth hormone deficiency refers to inadequate levels of GH (and therefore IGF-1), resulting in growth retardation in children and metabolic disturbances in adults.

ID

http://purl.obolibrary.org/obo/HP_0000824

comment

GH stimulation tests are performed with various stimuli, such as insulin, L-dopa, arginine, and growth hormone releasing hormone (GHRH). The test using insulin as a stimulus is classically recommended, but this test has potential risks such as hypoglycemia. The effects of growth hormone are mediated almost exclusively by insulin-like growth factor 1(IGF-1), which is produced primarily in the liver. Growth hormone deficiency refers to inadequate levels of GH (and therefore IGF-1), resulting in growth retardation in children and metabolic disturbances in adults.

label

Decreased response to growth hormone stimulation test

prefixIRI

HP:0000824

prefLabel

Decreased response to growth hormone stimulation test

subClassOf

http://purl.obolibrary.org/obo/HP_0000830

http://purl.obolibrary.org/obo/HP_0032367

http://purl.obolibrary.org/obo/HP_0031073

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