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Ontology of Adverse Events
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September 3, 2022
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| Id | http://purl.obolibrary.org/obo/UBERON_0002120
http://purl.obolibrary.org/obo/UBERON_0002120
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|---|---|
| Preferred Name | pronephros |
| Definitions |
In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO].
Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104
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| Synonyms |
pronephron
archinephron
embryonic kidney
pronephric kidney
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. |
|---|---|
| label |
pronephros
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| comment |
Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104
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| prefLabel |
pronephros
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| database_cross_reference |
EHDAA2:0001570
FMA:72170
XAO:0002000
AAO:0011089
BTO:0001541
ZFA:0000151
MIAA:0000117
TAO:0000151
EMAPA:16579
MAT:0000117
EFO:0000927
EHDAA:1017
VHOG:0000037
UMLS:C0231048
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|
| notation |
UBERON:0002120
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| in_subset | |
| has_related_synonym |
pronephron
archinephron
embryonic kidney
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| id |
UBERON:0002120
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| has_obo_namespace |
uberon
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| has_relational_adjective |
pronephric
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| external_definition |
The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion.Kimmel et al, 1995.[TAO]
A kidney formed of nephric tubules arising in the anterior region of the nephric ridge; forms only as a transient embryonic structure. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.748][VHOG]
Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.[AAO]
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| homology_notes |
In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG]
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| subClassOf | |
| imported from | |
| develops_from | |
| located_in | |
| has_alternative_id |
UBERON:0005794
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| type | |
| has_exact_synonym |
pronephric kidney
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