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Ontology of Adverse Events
Last uploaded:
April 7, 2026
| Id | http://purl.obolibrary.org/obo/UBERON_0001017
http://purl.obolibrary.org/obo/UBERON_0001017
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|---|---|
| Preferred Name | central nervous system |
| Definitions |
The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord.
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| Synonyms |
CNS
systema nervosum centrale
neuraxis
cerebrospinal axis
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. |
|---|---|
| label | central nervous system
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| prefLabel | central nervous system
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| has_narrow_synonym | cerebrospinal axis
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| never in taxon | |
| has_exact_synonym |
CNS
systema nervosum centrale
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| homology_notes | (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG]
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| has_obo_namespace | uberon
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| id | UBERON:0001017
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| database_cross_reference |
EV:0100163
XAO:0000215
CALOHA:TS-0150
MESH:D002490
TAO:0000012
MAT:0000457
BILA:0000080
EFO:0000908
ZFA:0000012
OpenCyc:Mx4rvzYt3pwpEbGdrcN5Y29ycA
FMA:55675
FBbt:00005094
EMAPA:16754
BAMS:CNS
GAID:570
EMAPA:16470
MA:0000167
AAO:0000090
VHOG:0000293
BTO:0000227
UMLS:C0927232
EHDAA2:0000225
EHDAA:828
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| external_definition | The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO).
The brain and spinal cord. Kimmel et al, 1995.[TAO]
Part of the nervous system which includes the brain and spinal cord.[AAO]
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| has_related_synonym | neuraxis
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| type | |
| subClassOf | |
| notation | UBERON:0001017
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