NanoParticle Ontology

Last uploaded: August 17, 2012
Preferred Name

folate antagonist

Synonyms

antifolate

folic acid inhibitor

folate inhibitor

folic acid antagonist

Definitions

<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic antimetabolite which interferes with folic acid metabolism by inhibiting one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. It has a chemical structure similar to folic acid, a key component in cell proliferation,</ncicp:def-definition></ncicp:ComplexDefinition>

ID

http://purl.bioontology.org/ontology/npo#NPO_460

code

NPO_460

dBXrefID

NCIT: C511

definition

<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic antimetabolite which interferes with folic acid metabolism by inhibiting one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. It has a chemical structure similar to folic acid, a key component in cell proliferation,</ncicp:def-definition></ncicp:ComplexDefinition>

label

folate antagonist

preferred_name

folate antagonist

prefixIRI

npo:NPO_460

synonym

antifolate

folic acid inhibitor

folate inhibitor

folic acid antagonist

subClassOf

http://purl.bioontology.org/ontology/npo#NPO_487

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