Preferred Name |
folate antagonist |
|
Synonyms |
antifolate folic acid inhibitor folate inhibitor folic acid antagonist |
|
Definitions |
<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic antimetabolite which interferes with folic acid metabolism by inhibiting one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. It has a chemical structure similar to folic acid, a key component in cell proliferation,</ncicp:def-definition></ncicp:ComplexDefinition> |
|
ID |
http://purl.bioontology.org/ontology/npo#NPO_460 |
|
code |
NPO_460 |
|
dBXrefID |
NCIT: C511 |
|
definition |
<ncicp:ComplexDefinition><ncicp:def-definition>Antineoplastic antimetabolite which interferes with folic acid metabolism by inhibiting one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. It has a chemical structure similar to folic acid, a key component in cell proliferation,</ncicp:def-definition></ncicp:ComplexDefinition> |
|
label |
folate antagonist |
|
preferred_name |
folate antagonist |
|
prefixIRI |
npo:NPO_460 |
|
synonym |
antifolate folic acid inhibitor folate inhibitor folic acid antagonist |
|
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.bioontology.org/ontology/CSP/1174-5583 | CRISP | LOOM | |
http://purl.obolibrary.org/obo/NCIT_C511 | BERO | LOOM | |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C511 | NCIT | LOOM |