loading...| Preferred Name |
apoptosis |
|
| Synonyms |
type I programmed cell death signaling (initiator) caspase activity apoptotic cell death programmed cell death by apoptosis apoptotic programmed cell death |
|
| Definitions |
A form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes. Apoptosis is usually induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. |
|
| ID |
http://purl.obolibrary.org/obo/GO_0006915 |
|
| database_cross_reference |
Reactome:255810 Reactome:280709 Reactome:265386 Wikipedia:Apoptosis Reactome:221788 Reactome:286733 Reactome:249908 Reactome:259206 Reactome:238478 Reactome:288390 Reactome:262565 Reactome:230365 Reactome:268517 Reactome:274243 Reactome:109581 Reactome:212025 Reactome:252627 Reactome:245020 |
|
| definition |
A form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes. Apoptosis is usually induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. |
|
| has_exact_synonym |
apoptotic cell death programmed cell death by apoptosis apoptotic programmed cell death |
|
| has_narrow_synonym |
type I programmed cell death |
|
| has_obo_namespace |
biological_process |
|
| has_related_synonym |
signaling (initiator) caspase activity |
|
| id |
GO:0006915 |
|
| label |
apoptosis |
|
| notation |
GO:0006915 |
|
| prefLabel |
apoptosis |
|
| treeView | ||
| subClassOf |