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Neuroscience Information Framework (NIF) Subcellular Ontology
| Preferred Name | Microfilament | |
| Synonyms |
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| Definitions |
A two-stranded helical polymer of the protein actin. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. Reference(s): ISBN:0198506732 PMID:10666339 (GO) |
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| ID |
http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Subcellular.owl#sao2006047981 |
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| curationStatus |
uncurated
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| definition |
A two-stranded helical polymer of the protein actin. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. Reference(s): ISBN:0198506732 PMID:10666339 (GO)
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| label |
Microfilament
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| prefixIRI |
sao2006047981
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| prefLabel |
Microfilament
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| sao_ID |
sao2006047981
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| umls_ID |
C0025979
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| disjointWith |
http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Subcellular.owl#sao952483289 |
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| subClassOf |
http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Subcellular.owl#sao1635329413 |
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