Preferred Name

circumventricular organ

Synonyms

circumventricular organ of neuraxis

circumventricular organ

CVO

Definitions

Any of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow.

ID

http://purl.obolibrary.org/obo/UBERON_0005408

database_cross_reference

neuronames:1242

MESH:D066280

EMAPA:35243

BTO:0006267

NLXANAT:20090312

Wikipedia:Circumventricular_organs

FMA:84081

MA:0002942

definition

Any of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow.

depiction

http://upload.wikimedia.org/wikipedia/commons/7/7d/Gray734.png

has exact synonym

circumventricular organ of neuraxis

circumventricular organ

CVO

has_obo_namespace

uberon

id

UBERON:0005408

in_subset

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

label

circumventricular organ

notation

UBERON:0005408

part_of

http://purl.obolibrary.org/obo/UBERON_0000955

prefLabel

circumventricular organ

structure_notes

CVOs contain neural tissue and are an integral part of neuroendocrine function; all of the CVOs, besides the subcommissural organ, contain extensive vasculature and fenestrated capillaries which leads to a leaky BBB at the site of the organs; the lack of a BBB allows CVOs to act as an alternative route for peptides and hormones in the neural tissue to the peripheral blood stream, while still protecting it from toxic substances

taxon_notes

All vertebrates possess at least 4 circumventricular organs (including the hypothalamus) which can monitor the contents of the cerebrospinal fluid and secrete additional substances into it. (Butler, 1996, p. 330)

treeView

http://purl.obolibrary.org/obo/UBERON_0000955

subClassOf

http://purl.obolibrary.org/obo/UBERON_0002616

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/UBERON_0005408 UBERON SAME_URI
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http://purl.obolibrary.org/obo/UBERON_0005408 NPOKB SAME_URI
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http://purl.obolibrary.org/obo/UBERON_0005408 CLO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0005408 DOID SAME_URI
http://purl.obolibrary.org/obo/UBERON_0005408 HHEAR SAME_URI
http://purl.obolibrary.org/obo/UBERON_0005408 OBA SAME_URI
http://purl.obolibrary.org/obo/UBERON_0005408 UPHENO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0005408 KTAO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0005408 MAXO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0005408 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/UBERON_0005408 FNS-H SAME_URI
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http://purl.obolibrary.org/obo/UBERON_0005408 CLO LOOM
http://purl.obolibrary.org/obo/UBERON_0005408 DOID LOOM
http://purl.obolibrary.org/obo/UBERON_0005408 HHEAR LOOM
http://purl.obolibrary.org/obo/UBERON_0005408 OBA LOOM
http://purl.obolibrary.org/obo/UBERON_0005408 UPHENO LOOM
http://purl.obolibrary.org/obo/UBERON_0005408 KTAO LOOM
http://purl.obolibrary.org/obo/UBERON_0005408 MAXO LOOM
http://purl.obolibrary.org/obo/UBERON_0005408 GO-PLUS LOOM
http://purl.obolibrary.org/obo/UBERON_0005408 FNS-H LOOM
http://purl.obolibrary.org/obo/BTO_0006267 BTO LOOM