loading...| Preferred Name |
lateral globus pallidus |
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| Synonyms |
pars lateralis globi pallidi medialis pallidus II lateral segment of globus pallidus globus pallidus externus lateral pallidal segment lateral part of globus pallidus external part of globus pallidus globus pallidus lateralis external globus pallidus lateral pallidum globus pallidus, lateral segment globus pallidus external segment globus pallidus extermal segment external pallidum globus pallidus, lateral part globus pallidus, external segment lateral division of globus pallidus globus pallidus lateral part globus pallidus (rat) pallidum dorsal region external segment globus pallidus lateral segment globus pallidus, pars externa nucleus lateralis globi pallidi lateral segment of the globus pallidus pallidum I |
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| Definitions |
The more lateral of the two segments of the [globus pallidus](http://knowledge-space.org/wiki/UBERON:0001875), abutting the putamen laterally in primates and the medial globus pallidus medially. It is also known as the external segment of the globus pallidus. It is distinguished from the [medial (internal) segment of the globus pallidus](http://knowledge-space.org/wiki/UBERON:0002477) by intense staining for enkephalin, due to a heavy projection from enkephalin-containing striatal medium spiny neurons ([DiFiacco et al., 1982](https://www.ncbi.nlm.nih.gov/pubmed/6275943)). The external segment of the globus pallidus is also distinguished by its efferent projections to the subthalamic nucleus, as opposed to the thalamus and substantia nigra. It is considered an integral part of the indiect pathway through the basal ganglia, in a model of basal ganglia circuitry first proposed by Albin and colleagues ([1989](https://www.ncbi.nlm.nih.gov/pubmed/2479133)). ## Delineations -Allen Mouse Brain Atlas (MBA): [Globus pallidus, external segment](http://knowledge-space.org/wiki/MBA:1022) The more lateral of the two segments of the globus pallidus, abutting the putamen. |
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| ID |
http://purl.obolibrary.org/obo/UBERON_0002476 |
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| database_cross_reference |
Wikipedia:Lateral_globus_pallidus neuronames:232 SCTID:361560008 EHDAA2:0004462 BTO:0002247 BIRNLEX:1610 EMAPA:37638 UMLS:C0262267 BAMS:EGP BAMS:GPe BAMS:GPl BAMS:LGP FMA:61839 HBA:12897 MA:0002767 MBA:1022 PBA:10099 |
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| definition |
The more lateral of the two segments of the [globus pallidus](http://knowledge-space.org/wiki/UBERON:0001875), abutting the putamen laterally in primates and the medial globus pallidus medially. It is also known as the external segment of the globus pallidus. It is distinguished from the [medial (internal) segment of the globus pallidus](http://knowledge-space.org/wiki/UBERON:0002477) by intense staining for enkephalin, due to a heavy projection from enkephalin-containing striatal medium spiny neurons ([DiFiacco et al., 1982](https://www.ncbi.nlm.nih.gov/pubmed/6275943)). The external segment of the globus pallidus is also distinguished by its efferent projections to the subthalamic nucleus, as opposed to the thalamus and substantia nigra. It is considered an integral part of the indiect pathway through the basal ganglia, in a model of basal ganglia circuitry first proposed by Albin and colleagues ([1989](https://www.ncbi.nlm.nih.gov/pubmed/2479133)). ## Delineations -Allen Mouse Brain Atlas (MBA): [Globus pallidus, external segment](http://knowledge-space.org/wiki/MBA:1022) |
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| delineatedBy | ||
| depiction |
https://upload.wikimedia.org/wikipedia/commons/e/ee/Brain_structure.gif |
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| external_definition |
The lateral globus pallidus (or external, GPe) receives a strong glutamatergic projection from the subthalamic nucleus. The two form a particular system: a coupled pacemaker. The axons of the external globus pallidum go essentially to the subthalamic nucleus. They go also to other elements of the basal ganglia system, the striatum, the substantia nigra pars reticulata, and the internal globus pallidus, where they release the neurotransmitter GABA. GPe is particular in comparison to the other elements of the set by the fact that it does not work as an output base of the basal ganglia (not sending axons to the thalamus) but as the main regulator of the basal ganglia system. It is sometimes used as a target for deep brain stimulation as a treatment for Parkinson's disease. [WP,unvetted][Wikipedia:Lateral_globus_pallidus]. |
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| has exact synonym |
pars lateralis globi pallidi medialis pallidus II lateral segment of globus pallidus globus pallidus externus lateral pallidal segment lateral part of globus pallidus external part of globus pallidus globus pallidus lateralis external globus pallidus lateral pallidum globus pallidus, lateral segment globus pallidus external segment globus pallidus extermal segment external pallidum |
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| has_obo_namespace |
uberon |
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| has_related_synonym |
globus pallidus, lateral part globus pallidus, external segment lateral division of globus pallidus globus pallidus lateral part globus pallidus (rat) pallidum dorsal region external segment globus pallidus lateral segment globus pallidus, pars externa nucleus lateralis globi pallidi lateral segment of the globus pallidus pallidum I |
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| id |
UBERON:0002476 |
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| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas |
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| label |
lateral globus pallidus |
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| notation |
UBERON:0002476 |
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| part_of | ||
| prefLabel |
lateral globus pallidus |
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| present_in_taxon | ||
| treeView | ||
| mutually_spatially_disjoint_with | ||
| disjointWith | ||
| subClassOf |