Preferred Name

zona incerta

Synonyms

zona incerta proper

nucleus of the zona incerta

Definitions

The zona incerta is a horizontally elongated region of gray matter cells in the subthalamus below the thalamus. Its connections project extensively over the brain from the cerebral cortex down into the spinal cord. Its function is unknown though several have been proposed related to 'limbic-motor integration' such as controlling visceral activity and pain; gating sensory input and synchronizing cortical and subcortical brain rhythms. Its dysfunction may play a role in central pain syndrome. It is also been identified as a promising deep brain stimulation therapy target for treating Parkinsons Disease. Its existence was first described by Auguste Forel in 1877 as a 'region of which nothing certain can be said'. A hundred and thirty years later in 2007, Nadia Urbain and Martin Deschênes of Université Laval noted that the 'zona incerta is among the least studied regions of the brain; its name does not even appear in the index of many textbooks. ' [WP,unvetted].

ID

http://purl.obolibrary.org/obo/UBERON_0001907

database_cross_reference

DHBA:10463

BM:Die-VTh-ZI

MBA:797

BAMS:ZI

FMA:62038

EMAPA:35930

BTO:0003146

HBA:4507

MA:0000878

http://www.snomedbrowser.com/Codes/Details/369186007

http://en.wikipedia.org/wiki/Zona_incerta

http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=438

delineatedBy

http://api.brain-map.org/api/v2/data/Structure/797

has_obo_namespace

uberon

has_related_synonym

zona incerta proper

nucleus of the zona incerta

id

UBERON:0001907

in_subset

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

zona incerta

notation

UBERON:0001907

prefLabel

zona incerta

textual definition

The zona incerta is a horizontally elongated region of gray matter cells in the subthalamus below the thalamus. Its connections project extensively over the brain from the cerebral cortex down into the spinal cord. Its function is unknown though several have been proposed related to 'limbic-motor integration' such as controlling visceral activity and pain; gating sensory input and synchronizing cortical and subcortical brain rhythms. Its dysfunction may play a role in central pain syndrome. It is also been identified as a promising deep brain stimulation therapy target for treating Parkinsons Disease. Its existence was first described by Auguste Forel in 1877 as a 'region of which nothing certain can be said'. A hundred and thirty years later in 2007, Nadia Urbain and Martin Deschênes of Université Laval noted that the 'zona incerta is among the least studied regions of the brain; its name does not even appear in the index of many textbooks. ' [WP,unvetted].

subClassOf

http://purl.obolibrary.org/obo/UBERON_0015234

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