Preferred Name

splenic cord

Synonyms

cord of Billroth

cord of Bilroth

Definitions

A structure found in the red pulp of the spleen between the sinusoids, consisting of fibrils and connective tissue cells with a large population of monocytes and macrophages. These cords contain half of the human body's monocytes as a reserve so that after tissue injury these monocytes can move in and aid locally sourced monocytes in wound healing. Erythrocytes pass through the cords of Billroth before entering the sinusoids. The passage into the sinusoids may be seen as a bottleneck, where erythrocytes need to be flexible in order to pass through. In disorders of erythrocyte shape and/or flexibility, such as hereditary spherocytosis, erythrocytes fail to pass through and get phagocytosed, causing extravascular hemolysis.

ID

http://purl.obolibrary.org/obo/UBERON_0001266

database_cross_reference

EMAPA:37752

Wikipedia:Cords_of_Billroth

UMLS:C0735011

NCIT:C33599

FMA:16031

MA:0002671

definition

A structure found in the red pulp of the spleen between the sinusoids, consisting of fibrils and connective tissue cells with a large population of monocytes and macrophages. These cords contain half of the human body's monocytes as a reserve so that after tissue injury these monocytes can move in and aid locally sourced monocytes in wound healing. Erythrocytes pass through the cords of Billroth before entering the sinusoids. The passage into the sinusoids may be seen as a bottleneck, where erythrocytes need to be flexible in order to pass through. In disorders of erythrocyte shape and/or flexibility, such as hereditary spherocytosis, erythrocytes fail to pass through and get phagocytosed, causing extravascular hemolysis.

has exact synonym

cord of Billroth

cord of Bilroth

has_obo_namespace

uberon

id

UBERON:0001266

in_subset

http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas

label

splenic cord

notation

UBERON:0001266

part_of

http://purl.obolibrary.org/obo/UBERON_0001250

prefLabel

splenic cord

present_in_taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606

treeView

http://purl.obolibrary.org/obo/UBERON_0001250

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000064

http://purl.obolibrary.org/obo/UBERON_0004120

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