loading...| Preferred Name | NMDA Receptor | |
| Synonyms |
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| Definitions |
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity (MSH). |
|
| ID |
http://uri.neuinfo.org/nif/nifstd/sao794753833 |
|
| definition |
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity (MSH). |
|
| editorial note |
uncurated |
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| externalSourceId |
C0080093 sao794753833 |
|
| hasCurationStatus |
uncurated |
|
| label |
NMDA Receptor |
|
| note |
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity (MSH). uncurated |
|
| preferred label |
NMDA Receptor |
|
| prefixIRI |
NIFSTD:sao794753833 |
|
| Resource Identifier |
C0080093 sao794753833 |
|
| sao_ID |
sao794753833 |
|
| umls_ID |
C0080093 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.jp/bio/4/id/200906052372310452 | IOBC | LOOM | |
| http://ccdb.ucsd.edu/SAO/1.2#sao794753833 | SAO | LOOM | |
| http://sbmi.uth.tmc.edu/ontology/ochv#C0080093 | OCHV | LOOM | |
| http://purl.bioontology.org/ontology/CSP/2573-3745 | CRISP | LOOM |