Preferred Name

AMPA Receptor
Synonyms
Definitions

Cell surface proteins that bind glutamate and directly gate ion channels in cell membranes. AMPA receptors were originally discriminated from other glutamate receptors by their affinity for the agonist AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid). They are probably the most common mediators of fast excitatory synaptic transmission in the central nervous system. Several subtypes have been cloned, and for some types the traditional distinction from kainate receptors may not apply (MSH).

ID

http://uri.neuinfo.org/nif/nifstd/sao265434492

definition

Cell surface proteins that bind glutamate and directly gate ion channels in cell membranes. AMPA receptors were originally discriminated from other glutamate receptors by their affinity for the agonist AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid). They are probably the most common mediators of fast excitatory synaptic transmission in the central nervous system. Several subtypes have been cloned, and for some types the traditional distinction from kainate receptors may not apply (MSH).

editorial note

uncurated

externalSourceId

C0072899

sao265434492

hasCurationStatus

uncurated

label

AMPA Receptor

note

Cell surface proteins that bind glutamate and directly gate ion channels in cell membranes. AMPA receptors were originally discriminated from other glutamate receptors by their affinity for the agonist AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid). They are probably the most common mediators of fast excitatory synaptic transmission in the central nervous system. Several subtypes have been cloned, and for some types the traditional distinction from kainate receptors may not apply (MSH).

uncurated

preferred label

AMPA Receptor

prefixIRI

NIFSTD:sao265434492

Resource Identifier

C0072899

sao265434492

sao_ID

sao265434492

umls_ID

C0072899

disjointWith

http://uri.neuinfo.org/nif/nifstd/sao794753833

subClassOf

http://uri.neuinfo.org/nif/nifstd/sao1164727693

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