loading...| Preferred Name |
Dopamine receptor |
|
| Synonyms |
DA DA receptor |
|
| Definitions |
Receptor that binds dopamine. These receptors are either D1-like receptors or D2-like receptors, where the D1 receptors (D1 and D5) increase adenylyl cyclase activity and the D2-like receptors (D2, D3, and D4) decrease adenylyl cyclase activity. The two families are distinguishable by expression patterns and pharmacology, and involved with different disease states. D1-like receptor family is involved with the brain's reward system and schizophrenia, while D2-like family is involved with motor control systems and Parkinsons disease. |
|
| ID |
http://uri.neuinfo.org/nif/nifstd/nifext_5832 |
|
| alternative label |
DA DA receptor |
|
| createdDate |
2007-09-19 |
|
| definition |
Receptor that binds dopamine. These receptors are either D1-like receptors or D2-like receptors, where the D1 receptors (D1 and D5) increase adenylyl cyclase activity and the D2-like receptors (D2, D3, and D4) decrease adenylyl cyclase activity. The two families are distinguishable by expression patterns and pharmacology, and involved with different disease states. D1-like receptor family is involved with the brain's reward system and schizophrenia, while D2-like family is involved with motor control systems and Parkinsons disease. |
|
| label |
Dopamine receptor |
|
| modifiedDate |
April 19, 2010 |
|
| note |
Receptor that binds dopamine. These receptors are either D1-like receptors or D2-like receptors, where the D1 receptors (D1 and D5) increase adenylyl cyclase activity and the D2-like receptors (D2, D3, and D4) decrease adenylyl cyclase activity. The two families are distinguishable by expression patterns and pharmacology, and involved with different disease states. D1-like receptor family is involved with the brain's reward system and schizophrenia, while D2-like family is involved with motor control systems and Parkinsons disease. |
|
| preferred label |
Dopamine receptor |
|
| prefixIRI |
NIFSTD:nifext_5832 |
|
| synonym |
DA DA receptor |
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| subClassOf |