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Id http://uri.neuinfo.org/nif/nifstd/birnlex_12686
http://uri.neuinfo.org/nif/nifstd/birnlex_12686
Preferred Name

Prion Disease
Definitions
A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES (MeSH).
Synonyms
Transmissible Dementia
Transmissible Spongiform Encephalopathy
Prion-Induced Disorder
Prion Protein Disease
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES (MeSH).
alternative label
Transmissible Dementia
Transmissible Spongiform Encephalopathy
Prion-Induced Disorder
Prion Protein Disease
preferred label
Prion Disease
label
Prion Disease
externalSourceId
D017096
_8.3_2.8
synonym
Transmissible Dementia
Transmissible Spongiform Encephalopathy
Prion-Induced Disorder
Prion Protein Disease
hasExternalSource
createdDate
October 5, 2007
note
A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES (MeSH).
http://uri.neuinfo.org/nif/nifstd/readable/uncurated
putativeClassExtension
Inherited Human Transmissible Spongiform Encephalopathy
usageNote
MeSH includes qualified subtype limiting to humans
hasCurationStatus
MeshUid
D017096
subClassOf
hasDefinitionSource
Resource Identifier
D017096
_8.3_2.8
hasBirnlexCurator
editorial note
type
modifiedDate
October 5, 2007
nifID
_8.3_2.8
definingCitation
Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83
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