Preferred Name

BMP
Synonyms
Definitions

A TGF-beta-like cystine-knot cytokine related to the transforming growth factor-beta, anti-Muellerian hormone, and activin/inhibin protein families, which are all involved in the regulation of cell growth and differentiation. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release bioactive the C-terminal peptide. BMP is involved in body patterning and morphogenesis. BMP signals are transmitted through specific type 2 and type 1 receptors. Category=family.

ID

http://purl.obolibrary.org/obo/PR_000000034

comment

Category=family.

database_cross_reference

PIRSF:PIRSF037272

definition

A TGF-beta-like cystine-knot cytokine related to the transforming growth factor-beta, anti-Muellerian hormone, and activin/inhibin protein families, which are all involved in the regulation of cell growth and differentiation. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release bioactive the C-terminal peptide. BMP is involved in body patterning and morphogenesis. BMP signals are transmitted through specific type 2 and type 1 receptors.

Category=family.

id

PR:000000034

label

BMP

notation

PR:000000034

note

A TGF-beta-like cystine-knot cytokine related to the transforming growth factor-beta, anti-Muellerian hormone, and activin/inhibin protein families, which are all involved in the regulation of cell growth and differentiation. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release bioactive the C-terminal peptide. BMP is involved in body patterning and morphogenesis. BMP signals are transmitted through specific type 2 and type 1 receptors.

Category=family.

preferred label

BMP

prefLabel

BMP

subClassOf

http://purl.obolibrary.org/obo/PR_000000008

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