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Preferred Name

mitogen-activated protein kinase
Synonyms

kinase-related transforming protein
Definitions

A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (mitogens) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY. Category=family.
ID

http://purl.obolibrary.org/obo/PR_000000019
comment

Category=family.
alternative label

kinase-related transforming protein
database_cross_reference

PIRSF:PIRSF501110
definition

A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (mitogens) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY.

Category=family.
has_related_synonym

kinase-related transforming protein
id

PR:000000019
label

mitogen-activated protein kinase
notation

PR:000000019
note

A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (mitogens) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY.

Category=family.
preferred label

mitogen-activated protein kinase
prefLabel

mitogen-activated protein kinase
subClassOf

http://purl.obolibrary.org/obo/PR_000000001

http://purl.obolibrary.org/obo/CHEBI_36080

http://uri.neuinfo.org/nif/nifstd/sao26622963
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