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Id http://purl.obolibrary.org/obo/CHEBI_10112
http://purl.obolibrary.org/obo/CHEBI_10112
Preferred Name

zileuton
Definitions
A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma.
Synonyms
N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea
(+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
Leutrol
Zyflo
N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea
zileutonum
zileuton
1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea
Zileuton
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma.
preferred label
zileuton
label
zileuton
prefLabel
zileuton
database_cross_reference
CAS:111406-87-2
LINCS:LSM-5084
DrugBank:DB00744
Reaxys:4869674
KEGG:D00414
PMID:20204486
PMID:19645854
Wikipedia:Zileuton
Drug_Central:2862
PMID:19309543
PMID:20436887
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notation
CHEBI:10112
in_subset
inchi
InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)
has_related_synonym
N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea
(+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
Leutrol
Zyflo
N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea
zileutonum
zileuton
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id
CHEBI:10112
note
A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma.
alternative label
N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea
(+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
Leutrol
Zyflo
N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea
zileutonum
zileuton
1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea
Zileuton
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charge
0
has_obo_namespace
chebi_ontology
formula
C11H12N2O2S
has parent hydride
subClassOf
inchikey
MWLSOWXNZPKENC-UHFFFAOYSA-N
mass
236.29126
monoisotopicmass
236.06195
type
smiles
CC(N(O)C(N)=O)c1cc2ccccc2s1
has role
has exact synonym
1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea
Zileuton
has characteristic
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