loading...| Preferred Name | professional antigen presenting cell | |
| Synonyms |
APC |
|
| Definitions |
A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. |
|
| ID |
http://purl.obolibrary.org/obo/CL_0000145 |
|
| comment |
Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. |
|
| alternative label |
APC |
|
| capable of | ||
| capable of part of | ||
| definition |
A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. |
|
| functionally related to | ||
| has_broad_synonym |
APC |
|
| in_subset |
http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim |
|
| label |
professional antigen presenting cell |
|
| note |
A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. |
|
| preferred label |
professional antigen presenting cell |
|
| prefixIRI |
CL:0000145 |
|
| prefLabel |
professional antigen presenting cell |
|
| subClassOf |