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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000181090
http://purl.bioontology.org/ontology/NDFRT/N0000181090
|
|---|---|
| Preferred Name | Lissencephaly [Disease/Finding] |
| Synonyms |
Lissencephalia
Lissencephaly
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Lissencephalia
Lissencephaly
|
|---|---|
| prefLabel | Lissencephaly [Disease/Finding]
|
| MESH DEFINITION | A smooth brain malformation of the CEREBRAL CORTEX resulting from the abnormal location of developing neurons during corticogenesis. It is characterized by an absence of normal convoluted indentations on the surface of the brain (agyria), or fewer and shallower indentations (pachygryia). There is a reduced number of cortical layers, typically 4 instead of 6, resulting in a thickened cortex, and reduced cerebral white matter that is a reversal of the normal ratio of cerebral white matter to cortex.
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| MESH DUI | D054082
|
| MESH UI | M0501372
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| MeSH name | Lissencephaly
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| type | |
| tui | T019
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| notation | N0000181090
|
| Semantic type UMLS property | |
| NUI | N0000181090
|
| cui | C0266463
|
| NDFRT kind | DISEASE_KIND
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |