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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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| Preferred Name | Perforin [Chemical/Ingredient] | |
| Synonyms |
Perforin Cytolysin Lymphocyte Pore-Forming Protein Perforin 1 |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000178600 |
|
| altLabel |
Perforin Cytolysin Lymphocyte Pore-Forming Protein Perforin 1
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|
| cui |
C0070410
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|
| MESH DEFINITION |
A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.
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|
| MESH DUI |
D054353
|
|
| MeSH name |
Perforin
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|
| MESH UI |
M0133732
|
|
| NDFRT kind |
INGREDIENT_KIND
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|
| notation |
N0000178600
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|
| NUI |
N0000178600
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|
| prefLabel |
Perforin [Chemical/Ingredient]
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|
| tui |
T116 T123
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| subClassOf |
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