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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000171441
http://purl.bioontology.org/ontology/NDFRT/N0000171441
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|---|---|
| Preferred Name | Conotoxins [Chemical/Ingredient] |
| Synonyms |
Conotoxin
Conotoxins
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Conotoxin
Conotoxins
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|---|---|
| prefLabel | Conotoxins [Chemical/Ingredient]
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| MESH DEFINITION | Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
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| MESH DUI | D020916
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| MESH UI | M0328109
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| MeSH name | Conotoxins
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| type | |
| tui |
T116
T131
T123
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| notation | N0000171441
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| Semantic type UMLS property | |
| NUI | N0000171441
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| cui | C0304176
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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