loading...| Preferred Name |
Proto-Oncogene Proteins c-kit [Chemical/Ingredient] |
|
| Synonyms |
SCF Receptor |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000171299 |
|
| altLabel |
SCF Receptor CD117 Antigens c-kit Protein Antigens, CD117 Receptor, Stem Cell Factor p145c-kit Proto-Oncogene Protein c-kit kit Proto-Oncogene Protein p145(c-kit) CD117 Antigen c-kit Receptor Proto-Oncogene Proteins c-kit Stem Cell Factor Receptor Proto-Oncogene Protein kit p145 c-kit |
|
| cui |
C0072470 |
|
| MESH DEFINITION |
A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis. |
|
| MESH DUI |
D019009 |
|
| MeSH name |
Proto-Oncogene Proteins c-kit |
|
| MESH UI |
M0028387 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000171299 |
|
| NUI |
N0000171299 |
|
| prefLabel |
Proto-Oncogene Proteins c-kit [Chemical/Ingredient] |
|
| tui |
T116 T129 T192 |
|
| subClassOf |