Preferred Name

Histocompatibility Antigens Class I [Chemical/Ingredient]
Synonyms

Class I Antigens

Class I Histocompatibility Antigens

Class I Major Histocompatibility Antigens

Histocompatibility Antigens Class I

ID

http://purl.bioontology.org/ontology/NDFRT/N0000171088

altLabel

Class I Antigens

Class I Histocompatibility Antigens

Class I Major Histocompatibility Antigens

Histocompatibility Antigens Class I

cui

C0019629

MESH DEFINITION

Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.

MESH DUI

D015395

MeSH name

Histocompatibility Antigens Class I

MESH UI

M0023721

NDFRT kind

INGREDIENT_KIND

notation

N0000171088

NUI

N0000171088

prefLabel

Histocompatibility Antigens Class I [Chemical/Ingredient]

tui

T116

T129

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000171087

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