loading...| Preferred Name |
Histocompatibility Antigens Class I [Chemical/Ingredient] |
|
| Synonyms |
Class I Antigens Class I Histocompatibility Antigens Class I Major Histocompatibility Antigens Histocompatibility Antigens Class I |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000171088 |
|
| altLabel |
Class I Antigens Class I Histocompatibility Antigens Class I Major Histocompatibility Antigens Histocompatibility Antigens Class I |
|
| cui |
C0019629 |
|
| MESH DEFINITION |
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells. |
|
| MESH DUI |
D015395 |
|
| MeSH name |
Histocompatibility Antigens Class I |
|
| MESH UI |
M0023721 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000171088 |
|
| NUI |
N0000171088 |
|
| prefLabel |
Histocompatibility Antigens Class I [Chemical/Ingredient] |
|
| tui |
T116 T129 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/MSHFRE/D015395 | MSHFRE | CUI | |
| http://purl.bioontology.org/ontology/CSP/2935-6332 | CRISP | CUI | |
| http://purl.bioontology.org/ontology/MESH/D015395 | MESH | CUI |