Preferred Name

Maturation-Promoting Factor [Chemical/Ingredient]

Synonyms

Histone H1 Kinase, Growth-Associated

Mitosis-Promoting Factor

Histone H1 Kinase, M-Phase-Specific

Maturation-Promoting Factor

M Phase-Promoting Factor

ID

http://purl.bioontology.org/ontology/NDFRT/N0000171013

altLabel

Histone H1 Kinase, Growth-Associated

Mitosis-Promoting Factor

Histone H1 Kinase, M-Phase-Specific

Maturation-Promoting Factor

M Phase-Promoting Factor

cui

C0079805

MESH DEFINITION

Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.

MESH DUI

D016200

MeSH name

Maturation-Promoting Factor

MESH UI

M0024733

NDFRT kind

INGREDIENT_KIND

notation

N0000171013

NUI

N0000171013

prefLabel

Maturation-Promoting Factor [Chemical/Ingredient]

tui

T116

T126

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000170541

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