Preferred Name |
Maturation-Promoting Factor [Chemical/Ingredient] |
|
Synonyms |
Histone H1 Kinase, Growth-Associated Mitosis-Promoting Factor Histone H1 Kinase, M-Phase-Specific Maturation-Promoting Factor M Phase-Promoting Factor |
|
ID |
http://purl.bioontology.org/ontology/NDFRT/N0000171013 |
|
altLabel |
Histone H1 Kinase, Growth-Associated Mitosis-Promoting Factor Histone H1 Kinase, M-Phase-Specific Maturation-Promoting Factor M Phase-Promoting Factor |
|
cui |
C0079805 |
|
MESH DEFINITION |
Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2. |
|
MESH DUI |
D016200 |
|
MeSH name |
Maturation-Promoting Factor |
|
MESH UI |
M0024733 |
|
NDFRT kind |
INGREDIENT_KIND |
|
notation |
N0000171013 |
|
NUI |
N0000171013 |
|
prefLabel |
Maturation-Promoting Factor [Chemical/Ingredient] |
|
tui |
T116 T126 |
|
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.bioontology.org/ontology/MESH/D016200 | MESH | CUI | |
http://purl.bioontology.org/ontology/MSHFRE/D016200 | MSHFRE | CUI | |
http://purl.bioontology.org/ontology/CSP/4001-0024 | CRISP | CUI |