loading...| Preferred Name |
Fibroblast Growth Factor 1 [Chemical/Ingredient] |
|
| Synonyms |
Class I Heparin-Binding Growth Factor |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000171006 |
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| altLabel |
Class I Heparin-Binding Growth Factor Heparin-Binding Growth Factor, Class I HBGF-1 FGF-1 Fibroblast growth factor (human brain acidic protein moiety reduced) Fibroblast Growth Factor-1 Acidic Fibroblast Growth Factor Fibroblast Growth Factor, Acidic FGF1 Fibroblast Growth Factor 1 Heparin-Binding Fibroblast Growth Factor Class I |
|
| cui |
C0079349 |
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| MESH DEFINITION |
A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2). |
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| MESH DUI |
D016220 |
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| MeSH name |
Fibroblast Growth Factor 1 |
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| MESH UI |
M0024768 |
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| NDFRT kind |
INGREDIENT_KIND |
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| notation |
N0000171006 |
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| NUI |
N0000171006 |
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| prefLabel |
Fibroblast Growth Factor 1 [Chemical/Ingredient] |
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| tui |
T116 T123 |
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| subClassOf |