Preferred Name

Vascular Endothelial Growth Factor A [Chemical/Ingredient]
Synonyms

Vascular Permeability Factor

Vascular Endothelial Growth Factor

VEGF-A

Vascular Endothelial Growth Factor-A

Vasculotropin

VEGF

Vascular Endothelial Growth Factor A

ID

http://purl.bioontology.org/ontology/NDFRT/N0000170972

altLabel

Vascular Permeability Factor

Vascular Endothelial Growth Factor

VEGF-A

Vascular Endothelial Growth Factor-A

Vasculotropin

VEGF

Vascular Endothelial Growth Factor A

cui

C0078058

MESH DEFINITION

The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.

MESH DUI

D042461

MeSH name

Vascular Endothelial Growth Factor A

MESH UI

M0356369

NDFRT kind

INGREDIENT_KIND

notation

N0000170972

NUI

N0000170972

prefLabel

Vascular Endothelial Growth Factor A [Chemical/Ingredient]

tui

T116

T123

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000170971

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