Link to this page
National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
Jump to:
Preferred Name | Vascular Endothelial Growth Factor A [Chemical/Ingredient] | |
Synonyms |
Vascular Permeability Factor Vascular Endothelial Growth Factor VEGF-A Vascular Endothelial Growth Factor-A Vasculotropin VEGF Vascular Endothelial Growth Factor A |
|
ID |
http://purl.bioontology.org/ontology/NDFRT/N0000170972 |
|
altLabel |
Vascular Permeability Factor Vascular Endothelial Growth Factor VEGF-A Vascular Endothelial Growth Factor-A Vasculotropin VEGF Vascular Endothelial Growth Factor A
|
|
cui |
C0078058
|
|
MESH DEFINITION |
The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
|
|
MESH DUI |
D042461
|
|
MeSH name |
Vascular Endothelial Growth Factor A
|
|
MESH UI |
M0356369
|
|
NDFRT kind |
INGREDIENT_KIND
|
|
notation |
N0000170972
|
|
NUI |
N0000170972
|
|
prefLabel |
Vascular Endothelial Growth Factor A [Chemical/Ingredient]
|
|
tui |
T116 T123
|
|
subClassOf |
Add comment
Delete | Subject | Author | Type | Created |
---|---|---|---|---|
No notes to display |
Create mapping