loading...| Preferred Name | RNA, Small Interfering [Chemical/Ingredient] | |
| Synonyms |
Small Interfering RNA siRNA RNA, Small Interfering Short Interfering RNA |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000170714 |
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| altLabel |
Small Interfering RNA siRNA RNA, Small Interfering Short Interfering RNA |
|
| cui |
C1099354 |
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| MESH DEFINITION |
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions. |
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| MESH DUI |
D034741 |
|
| MeSH name |
RNA, Small Interfering |
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| MESH UI |
M0406100 |
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| NDFRT kind |
INGREDIENT_KIND |
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| notation |
N0000170714 |
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| NUI |
N0000170714 |
|
| prefLabel |
RNA, Small Interfering [Chemical/Ingredient] |
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| tui |
T123 T114 |
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| subClassOf |