loading...| Preferred Name |
eIF-2 Kinase [Chemical/Ingredient] |
|
| Synonyms |
p68 Kinase eIF-2 Kinase Self-Phosphorylating Protein Kinase Heme-Regulated eIF-2alpha Kinase DAI Protein Kinase DSRNA-Dep Protein Kinase TIK Kinase RNA-Dependent Protein Kinase Heme Controlled Repressor dsRNA-Activated Inhibitor Heme-Controlled Translational Repressor P68 Protein Kinase eRF, eIF-2 Recycling Factor Protein Kinase, RNA Activated Heme-Controlled Inhibitor p65 Kinase Protein Kinase PKR eIF-2alpha Kinase Hemin Controlled Repressor Double Stranded RNA-Dependent eIF-2 alpha Protein Kinase Eukaryotic Initiation Factor 2alpha Kinase Hemin-Controlled Translational Repressor Double Stranded RNA-Dependent Kinase (dsl) |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000170522 |
|
| altLabel |
p68 Kinase eIF-2 Kinase Self-Phosphorylating Protein Kinase Heme-Regulated eIF-2alpha Kinase DAI Protein Kinase DSRNA-Dep Protein Kinase TIK Kinase RNA-Dependent Protein Kinase Heme Controlled Repressor dsRNA-Activated Inhibitor Heme-Controlled Translational Repressor P68 Protein Kinase eRF, eIF-2 Recycling Factor Protein Kinase, RNA Activated Heme-Controlled Inhibitor p65 Kinase Protein Kinase PKR eIF-2alpha Kinase Hemin Controlled Repressor Double Stranded RNA-Dependent eIF-2 alpha Protein Kinase Eukaryotic Initiation Factor 2alpha Kinase Hemin-Controlled Translational Repressor Double Stranded RNA-Dependent Kinase (dsl) |
|
| cui |
C0058980 |
|
| MESH DEFINITION |
A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, the kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of EUKARYOTIC INITIATION FACTOR-2, leading to the inhibition of protein synthesis. |
|
| MESH DUI |
D019892 |
|
| MeSH name |
eIF-2 Kinase |
|
| MESH UI |
M0029534 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000170522 |
|
| NUI |
N0000170522 |
|
| prefLabel |
eIF-2 Kinase [Chemical/Ingredient] |
|
| tui |
T116 T126 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/MESH/D019892 | MESH | CUI | |
| http://purl.bioontology.org/ontology/MSHFRE/D019892 | MSHFRE | CUI | |
| http://purl.bioontology.org/ontology/CSP/2312-2490 | CRISP | CUI |