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loading...| Preferred Name |
Proinsulin [Chemical/Ingredient] |
|
| Synonyms |
Proinsulin |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000170325 |
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| altLabel |
Proinsulin |
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| cui |
C0033362 |
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| MESH DEFINITION |
A pancreatic polypeptide of about 110 amino acids, depending on the species, that is the precursor of insulin. Proinsulin, produced by the PANCREATIC BETA CELLS, is comprised sequentially of the N-terminal B-chain, the proteolytically removable connecting C-peptide, and the C-terminal A-chain. It also contains three disulfide bonds, two between A-chain and B-chain. After cleavage at two locations, insulin and C-peptide are the secreted products. Intact proinsulin with low bioactivity also is secreted in small amounts. |
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| MESH DUI |
D011384 |
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| MeSH name |
Proinsulin |
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| MESH UI |
M0017685 |
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| NDFRT kind |
INGREDIENT_KIND |
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| notation |
N0000170325 |
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| NUI |
N0000170325 |
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| prefLabel |
Proinsulin [Chemical/Ingredient] |
|
| tui |
T116 T123 |
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| subClassOf |
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