loading...| Preferred Name | Steroid 17-alpha-Hydroxylase [Chemical/Ingredient] | |
| Synonyms |
Cytochrome P-450(17-alpha) Cytochrome P-450(17 alpha) CYP17 17 alpha-Hydroxylase Cytochrome P-450 Steroid 17-alpha-Hydroxylase P450(c17) 17,20-Desmolase Steroid 17-Hydroxylase 17,20-Lyase Steroid 17-Monooxygenase Steroid 17 alpha-Monooxygenase Steroid-17-Hydroxylase Cytochrome P450(17 alpha) Steroid 17 alpha-Hydroxylase 17 alpha-Hydroxylase Steroid, hydrogen-donor:oxygen oxidoreductase (17 alpha-hydroxylating) |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000170031 |
|
| altLabel |
Cytochrome P-450(17-alpha) Cytochrome P-450(17 alpha) CYP17 17 alpha-Hydroxylase Cytochrome P-450 Steroid 17-alpha-Hydroxylase P450(c17) 17,20-Desmolase Steroid 17-Hydroxylase 17,20-Lyase Steroid 17-Monooxygenase Steroid 17 alpha-Monooxygenase Steroid-17-Hydroxylase Cytochrome P450(17 alpha) Steroid 17 alpha-Hydroxylase 17 alpha-Hydroxylase Steroid, hydrogen-donor:oxygen oxidoreductase (17 alpha-hydroxylating) |
|
| cui |
C0038302 |
|
| MESH DEFINITION |
A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation. |
|
| MESH DUI |
D013254 |
|
| MeSH name |
Steroid 17-alpha-Hydroxylase |
|
| MESH UI |
M0020523 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000170031 |
|
| NUI |
N0000170031 |
|
| prefLabel |
Steroid 17-alpha-Hydroxylase [Chemical/Ingredient] |
|
| tui |
T116 T126 |
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| subClassOf |