loading...| Preferred Name | Cytochrome P-450 Enzyme System [Chemical/Ingredient] | |
| Synonyms |
Cytochrome P-450 Enzyme System Cytochrome P-450 Enzymes Cytochrome p450 Families Cytochrome P-450 Cytochrome P-450 Families Cytochrome P 450 Cytochrome P450 Cytochrome P-450 Superfamily P-450 Enzymes Cytochrome P450 Superfamily CYP450 Superfamily CYP450 Family P450 Enzymes |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000170028 |
|
| altLabel |
Cytochrome P-450 Enzyme System Cytochrome P-450 Enzymes Cytochrome p450 Families Cytochrome P-450 Cytochrome P-450 Families Cytochrome P 450 Cytochrome P450 Cytochrome P-450 Superfamily P-450 Enzymes Cytochrome P450 Superfamily CYP450 Superfamily CYP450 Family P450 Enzymes |
|
| cui |
C0010762 |
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| MESH DEFINITION |
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. |
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| MESH DUI |
D003577 |
|
| MeSH name |
Cytochrome P-450 Enzyme System |
|
| MESH UI |
M0005591 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000170028 |
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| NUI |
N0000170028 |
|
| prefLabel |
Cytochrome P-450 Enzyme System [Chemical/Ingredient] |
|
| tui |
T116 T126 |
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| subClassOf |