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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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| Preferred Name | Keratins [Chemical/Ingredient] | |
| Synonyms |
Keratin Keratins Cytokeratin |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000169473 |
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| altLabel |
Keratin Keratins Cytokeratin
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|
| cui |
C0010803
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| MESH DEFINITION |
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
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| MESH DUI |
D007633
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|
| MeSH name |
Keratins
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|
| MESH UI |
M0011957
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|
| NDFRT kind |
INGREDIENT_KIND
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|
| notation |
N0000169473
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|
| NUI |
N0000169473
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|
| prefLabel |
Keratins [Chemical/Ingredient]
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|
| tui |
T116
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| subClassOf |
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